NATURPHARMA GINEXID cleansing foam menopause 150ml
Ginexid Menopause is a new thick and refreshing intimate foam with a specially adapted pH of 6 for the needs of the changing female body. It cleanses gently and is well tolerated even with prolonged daily use thanks to the formula without aggressive surfactants.
Formulated with natural extracts of oats, witch hazel and chamomile, plus panthenol, Ginexide Menopause supports your self-confidence and comfort during the new stage of your life. The active ingredients of this delicate foam have a pronounced anti-inflammatory, antifungal, soothing and refreshing effect, maintain hydration and contribute to the decongestion of the vaginal environment.
Created in Italy with the same care and scientific precision as the intimate hygiene favorite Ginexide, the new cleansing foam is here to preserve your flawless femininity through menopause.
Features:
· Thick and refreshing daily care, suitable for long-term use.
· With natural extracts of oats, witch hazel and chamomile, plus panthenol.
· Soothes, hydrates and cleanses delicately without aggressive surfactants.
· With pH 6 adapted to the physiology of the female body during menopause.
· Created with scientific precision and human care in Italy.
· With the quality that makes women prefer the leader in intimate hygiene, Ginexid.
· Dermatologically tested.
· No ozone-depleting propellants.
Composition:
Aqua, Cocamidopropyl Betaine, Butane, Coco-Glucoside, Sodium Lauroyl Sarcosinate, Chamomilla Recutita Flower Water, Hamamelis Virginiana Leaf Water, Isobutane, Propane, Glycerin, Parfum, Sodium Chloride, Sodium Cocoyl Hydrolyzed Wheat Protein, Phenoxyethanol, PEG-12, Dimethicone, Panthenol, Disodium Cocoyl Glutamate, Lactic Acid, Avena Sativa Leaf Extract, Chlorhexidine Digluconate, Menthol, Saccharomyces Ferment Lysate Filtrate, Citric Acid, Ethylhexylglycerin, Tetrasodium Glutamate Diacetate, Sodium Benzoate, Potassium Sorbate.
Method of use:
Shake the bottle well before use and keep it upright during dosing. Clean the external genitalia and rinse with water.
Packaging: 150 ml
Active ingredients in the care of intimate hygiene and comfort during menopause
Menopause is a stage in a woman's life characterized by a decline in estrogen levels. This is associated with a number of changes in genital tissues, including thinning of the vaginal epithelium, increased connective tissue, decreased blood flow to the vagina, and loss of elasticity (Lester & Bernhard, 2009; Mac Bride, Rhodes, & Shuster, 2010).
Known among specialists as genitourinary syndrome of menopause, this set of anatomical and functional changes is characterized by vaginal dryness, burning, irritation, pain, and light bleeding after intercourse, and in complications can lead to painful urination and recurrent urinary infections such as cystitis (Nappi & Palacios, 2014; Lev-Sagie, 2015).
Thinning of the vaginal mucosa is also associated with reduced desquamation of glycogen-rich epithelial cells. This leads to reduced lactic acid production by vaginal lactobacilli and an increase in vaginal pH from the usual premenstrual range (3.5–4.5) to values between 5.0 and 7.5 (average around 6) (Caillouette et al., 2007).
This acidity, although normal for the menopausal period, allows for the freer development of pathogenic bacterial flora (Roy et al., 2004; Lev-Sagie, 2015) and makes the woman more prone to bacterial vaginosis and vaginal candidiasis (Brotman et al., 2014).
All this requires changes in the usual care of the intimate area and emphasizes the importance of using appropriate intimate hygiene products. That is why we created Ginexid Menopause - an intimate cleansing foam with a carefully selected combination of researched active ingredients that maintain a woman's comfort and self-confidence during the new stage of her life.
Chamomile extract
Chamomile is one of the oldest medicinal plants known to mankind. It contains over 120 substances with therapeutic potential, and folk medicine and modern science have found it to be particularly effective for wounds, ulcers, inflammation, burns, and skin irritations.
On the intimate health front, chamomile extract stands out as one of the most promising natural remedies for combating the most common gynecological disease – inflammation of the vagina, also known as vaginitis or colpitis (Srivastava, Shankar & Gupta, 2010; Benetti & Manganelli, 1985).
Witch hazel extract
Witch hazel is one of the most well-known astringents and antiseptics in traditional medicine and modern dermatology. Thanks to its high tannin content, it acts as a natural tonic, tightening the skin and shrinking pores.
This makes it particularly good for reducing skin irritation, itching, burning, and the risk of infection from chafing or shaving. Its anti-inflammatory properties contribute to its soothing effect, and the temporary tightening effect in the intimate area is a pleasant sensory bonus (Van Wyk & Wink, 2018; Thring, Hili & Naughton, 2011).
Panthenol
Panthenol is a derivative of pantothenic acid (vitamin B5) – a member of the B-group vitamins and an essential component for the normal function of epithelial tissue. It is also a starting product for the formation of coenzyme A, which plays the role of a cofactor in a number of enzymatic reactions involved in protein metabolism in the epithelium.
Dermatological effects of topical panthenol include increased formation of fibroblasts – cells that produce key components for tissue tone and health, such as collagen, elastin and hyaluronic acid. In addition, panthenol plays a local protective and moisturizing role and has pronounced anti-inflammatory and soothing properties (Biro et al., 2003; Proksch et al., 2007).
In gynecology, the moisturizing properties of panthenol have been tested for vaginal dryness since at least the middle of the last century (Langer, 1960). Even then, its role as a humectant was well known, meaning that it binds and retains significant amounts of water – all important qualities when we talk about the health, softness, tone, elasticity and comfort of the skin and mucous membranes.
In recent years, studies have also shown that the substance significantly reduces water loss. A product with only 1% panthenol content not only has an instant moisturizing effect, but also protects the skin from drying out even when using aggressive surfactants such as SLES (Camargo et al., 2011).
Last but not least, the emollient properties of panthenol can stimulate the synthesis of lipids in the skin. This strengthens the skin barrier, which contains natural fats with protective functions both against water loss and against invasions of allergens and pathogens from the environment (Ebner et al., 2002; Pavlačková et al., 2019).
Oat extract
Records of the use of oats for various skin conditions date back to the Roman Empire, and scientific publications on its dermatological effectiveness began to appear in the early 20th century. Since then, various extracts of the plant have been tested and used for dry skin (Smith, 1958).
In 2003, the US Food and Drug Administration approved claims for its skin-protective properties, and in parallel, a number of reports accumulated regarding its effectiveness in rashes, erythema, burns, itching, and eczema (Cerio et al., 2010).
Despite its extensive record of dermatological benefits, the exact mechanism of action behind the clinical effects of oats remains poorly understood. Subsequently, evidence began to emerge that oats reduce levels of pro-inflammatory mediators in the skin, which is likely responsible for their soothing properties in skin irritations (Reynertson et al., 2015).
Other studies have demonstrated that oats can increase the expression of genes that increase ceramide levels in skin cells, which is reflected in the improvement and restoration of tissue barrier function (Chon et al., 2015).
Extracts from the plant have been found to improve epidermal cell differentiation and skin lipid regulation, as well as tissue resistance to changes in acidity (Garay et al., 2016).
In 2021, it was discovered that oat extract protects skin cells from cell death resulting from oxidative stress, which is due to its rich content of substances with antioxidant activity – polyphenols, avenanthramides, γ-oryzanols, tocotrienols, and carotenoids (Song et al., 2021).
Studies on the safety of oat extract products are conclusive. Among users of 445,820 cosmetic products over a 3-year period, no allergic reactions were reported. Combined with the low irritant potential of the ingredient, this leads scientists to conclude that oat extract is a safe and effective cosmetic ingredient (Criquet et al., 2012).
Chlorhexidine
Chlorhexidine gluconate is one of the most widely used vaginal antiseptics with proven activity against a large number of microbes associated with the development of gynecological infections. It has been shown that the compound begins to act immediately and inhibits bacterial growth for up to 24 hours after application.
Unlike other antiseptics, its activity is not affected by typical hygiene product ingredients such as alcohol and surfactants, as well as by the low pH characteristic of the vagina.
Its safety has been confirmed in a wide range of concentrations (0.05–4%), including intravaginal use to reduce infections in parturient women in obstetric settings (Vorherr et al., 1980; Dykes et al., 1983; Molteni et al., 2004; Ferris et al., 2006; Bell et al., 2018).
Lactic acid
Lactic acid is of fundamental importance for women's intimate health. It contributes to the specific acidity of the vagina, and its adequate levels are one of the conditions for the prevention of bacterial vaginosis.
Its antibacterial effect against common pathogens such as chlamydia (Chlamydia trachomatis), gonorrhea (Neisseria gonorrhoeae), gardnerella (Gardnerella vaginalis), Escherichia coli and group B streptococci (Streptococcus agalactiae) has been scientifically confirmed.
It has been found that the vaginal microbiota rich in lactic acid bacteria has a preventive role against the AIDS and herpes viruses. The reason for this lies in the lactic acid produced by them, which has high HIV and HSV (herpes simplex virus) virucidal activity. Lactic acid also has well-studied anti-inflammatory and immunomodulatory properties (Tachedjian, 2017).
Menthol
We all know that menthol cools. But how does this happen? The decrease in ambient temperature, which we feel as “cold”, is registered by our nervous system with the help of so-called TRPM8 receptors. Capturing the signal from the environment, these tiny specialized cells send an instant signal to our brain and so we quickly realize that it has become cold outside.
Menthol cools us in exactly the same way because it has the unique property of binding to our TRPM8 receptors and activating them. In this way, our brain experiences the well-known sensation of cold, with the important difference that we can choose where and when we feel cold and the particular advantage that there is no risk of frostbite (McKemy, 2007).
Combined with the astringent effect of witch hazel, menthol can help relieve burning, tone tissue, and improve comfort in the intimate area.
WARNINGS: Caution. Pressurized container: may burst if heated. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not pierce or burn, even after use. Keep out of direct sunlight. Do not expose to temperatures exceeding 50°C/122°F. Keep out of reach of children. 8% of all components by weight are flammable. Avoid contact with eyes. Do not swallow. For external use only.
Manufacturer: FARMA-DERMA srl Via dell'Artigiano 6-8 40010 Sala Bolognese (BO) - Italy
Distributor: Naturpharma Bulgaria EOOD Sofia 1164, 21 Yanko Sofiyski Str.
