TOP FOLATE 400mg x 60 tabl
TOP FOLATE capsules 0.400 mg * 30
Product description:
Folate is involved in the synthesis of neurotransmitters and in critical enzymatic reactions throughout the body. By removing excess homocysteine, it has an extremely beneficial effect on cardiovascular health and nervous system function. Taking folic acid during pregnancy has been shown to reduce the risk of birth defects.
Research shows that in a large proportion of people, a genetic enzyme deficiency prevents the conversion of folic acid to 5-MTHF, which is why many of them are left with low levels of folate in the blood (and higher than desired levels of homocysteine).
5-MTHF Quatrefolic is no longer considered a drug and is available as a dietary supplement. There is evidence that 5-MTHF Quatrefolic dramatically increases the concentration of folate in red blood cells compared to folic acid supplements. This bioactive folate has up to seven times greater bioavailability than folic acid. This is especially important for people who have a genetic deficiency of folic acid-metabolizing enzymes, as it does not need to be converted to become metabolically active.
(6S)-5-methyltetrahydrofolate or (6S)-5-MTHF is the most biologically active form of vitamin B9 available on the market today. In addition to genetic defects, the transformation of folic acid into the active form of folate can also be compromised by physiological stress, as well as an inappropriate lifestyle.
The best solution is to take the bioactive folate 5-MTHF Quatrefolic directly.
Unlike folic acid, 5-MTHF like Quatrefolic can cross the blood-brain barrier. This is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain - a neurotransmitter associated with memory. Studies also show that the effectiveness of 5-MTHF Quatrefolic can be further enhanced by supplementing with methylcobalamin (the active form of vitamin B12), vitamin B6 and riboflavin.
Healthy diets with adequate intake of 5-MTHF Quatrefolic can reduce the risk of having a child with spinal cord defects. Scientific research in recent years has proven the advantages of the reduced form of folate over folic acid. The use of reduced forms of folate (reduced and methylated) is essential for people who cannot assimilate and metabolize folic acid from food and supplements.
A problem with reduced and methylated folates is that they have limited stability. Therefore, they need to be stored at low temperatures to avoid the formation of undesirable compounds due to the high activity of the molecules. The second problem is their reduced bioavailability due to poor solubility.
Quatrefolic is the latest fourth generation folate derivative, consisting of (6S)-5-methyltetrahydrofolate and glucosamine salt. This form allows overcoming the problems associated with the application of the existing calcium salt of folate - stability, poor solubility and bioavailability. Four key factors of critical importance make Quatrefolic an extremely successful product. They are: bioavailability, safety, stability and multifunctionality of the formula.
With the development of Quatrefolic, Gnosis introduces an unknown concept in the field of folate compounds: the creation of a folate form that is simultaneously active, stable, highly soluble and highly bioavailable. This is something that has not been achieved before with folic acid and other methylfolate derivatives.
Purpose: TOP FOLATE contains fourth generation folate, patented under the name Quatrefolic. Quatrefolic does not require metabolism. It is identical to the bioactive form of folic acid in the body. It is a pure, stable glucosamine salt of Methyltetrahydrofolic acid. (6S)-5-Methyltetrahydrofolate (MTHF) is of fundamental importance for metabolic processes in the body.
Capsule type: cellulose of plant origin, suitable for vegetarians.
Recommended daily dose: 1 capsule per day or as recommended by your doctor.
Recommended time of intake: between meals.
Duration of use: for optimal effect, it is recommended to take the product for a long time.
Composition of 1 capsule: Contents in 1 capsule recommended daily dose
0.400 g in the form of (6S)-5-Methyltetrahydrofolate (MTHF) 0.400 μg 100%
0.800 g (6S)-5-Methyltetrahydrofolate, glucosamine salt vegetarian source/
Ingredients: Silicon dioxide, magnesium stearate /vegetable origin/, vegetable cellulose.
A product suitable for vegans and vegetarians.
Contraindications: none known.
Storage: in a dry and cool place. Do not use after the expiration date!
Warning: Do not exceed the recommended daily dose. The product is not a substitute for a varied diet. Food supplement.
Packaging: 30 capsules.
Manufacturer: Plantapol SL, Spain.
Importer: "VIVAPHARMA SOLUTIONS" Ltd., Bulgaria
