NATURPHARMA PEANIL for chronic pain x 15 caps

NATURPHARMA PEANIL for chronic pain x 15 caps

Peanil is a combined preparation with palmitoylethanolamide (PEA) and L-ascorbic acid (vitamin C), which contributes to the normal functioning of the nervous and immune systems, to the protection of cells from oxidative stress and to the reduction of the feeling of exhaustion and fatigue. Unlike non-steroidal anti-inflammatory drugs commonly used for pain problems, the effect of Peanil manifests itself over time and is permanent (its active ingredients act cumulatively), and its use does not pose serious risks such as ulcerogenicity (development of ulcers), nephrotoxicity (damage to kidneys) and bronchospasticity (constriction of the bronchial walls leading to shortness of breath). Composition (in 1 capsule): Palmitoylethanolamide (micronized and ultramicronized) 400 mg Vitamin C (L-ascorbic acid) 300 mg Recommended dosage: Take 1 Peanil capsule about 30 minutes before meals in the morning and evening for a period of 2 weeks, then 1 capsule daily for a period of 30-60 days. If necessary, the dose can be increased again to 2 capsules per day, and the duration of administration can be extended. Package: 15 capsules Chronic pain and mechanism of action of Peanil Chronic pain affects about 20% of the population and increases with age, reaching epidemic proportions of 45% to 80% in older people. The normal process of the body's reaction to various irritants is carried out through acute pain. It is caused by an external stimulus, which turns into electrical activity in the sensory neurons, and after transmission from one neuron to another, the signal reaches the brain, where, in reverse order, with the help of neurotransmitters, the transmission of pain stimuli is inhibited and the pain subsides and disappears. Unlike acute pain, chronic pain is usually associated with neurogenic inflammation, which causes nerves to become damaged and begin to send repetitive pain signals like a broken alarm. As a result of all this, the pain signal cannot be turned off, and the pain becomes more and more intense. Although pain is processed by the nervous system, the immune system also contributes to creating hypersensitivity in chronic pain. For example, immune cells called mast cells and microglia are activated. This immune activation causes the release of mediators from mast cells located near the nerve endings, leading to an increase in the sensitivity of peripheral pain receptors and an increased response by neurons in the central nervous system. Due to the impossibility of suppressing this process, chronic inflammation and chronic pain are reached. Palmitoylethanolamide (PEA) is a substance that is formed normally in the body when its cells or tissues are subjected to harmful effects, stress or trauma. It has been found that PEA inhibits the release of inflammatory mediators from immune cells and thus reduces inflammation of nerve tissue and exerts an anti-pain effect. When chronic pain occurs, however, the amount of PEA that the body produces on its own is insufficient and it has to be taken from the outside. The effects of PEA as an anti-inflammatory and pain-relieving therapy have been proven in more than 30 clinical studies with over 6,000 patients. Vitamin C is a powerful antioxidant that reduces the harmful effects of free radicals formed during inflammation of nerve tissue and thus protects it. In addition to these effects, in recent years it has been found that vitamin C stimulates the formation of certain substances in the body that exert an anti-pain effect. Such natural substances for the body are endorphins, which are also called "hormones of happiness" because they reduce pain, exert an anti-inflammatory effect and lead to an improvement in the condition. Contraindications: Do not use during pregnancy, breastfeeding and by children under 6 years of age. Do not use in case of hypersensitivity to any of the ingredients. Warnings: Do not exceed the recommended daily dose! The nutritional supplement should not be used as a substitute for a varied diet! Keep out of the reach of small children! Storage conditions: Store in a dry place at room temperature. Manufacturer: Plantapol SL · Pol. Ind. Malpica Alfindén, G 18 50171 - La Puebla de Alfindén, Zaragoza (Spain) Distributor: Naturpharma Bulgaria EOOD, Sofia, ul. Yanko Sofiyski 21, phone: 02/963 33 59, info@naturpharmabg.com