NATURPHARMA THYROHELP SLIM for the thyroid gland x 30 caps
THYROHELP SLIM thyroid care and normal weight 30 capsules
Thyrohelp Slim is an enriched formula with a focus on thyroid health, normal body weight and immune function. Its action is due to a precisely selected combination of ingredients that complement and enhance each other.
Selenium for normal thyroid function is fortified with L-tyrosine and turmeric. Natural apple cider vinegar and ginger extract are added, the effect of which on body weight and appetite has been the subject of numerous clinical trials.
The combination of zinc and vitamin D has been proven to contribute to the normal function of the immune system.
Active ingredients:
Quantity in 1 capsule:
1 capsule delivers:
L-tyrosine
250 mg
Ginger extract (Zingiber officinale Roscoe, root) (min. 5% gingerols)
100 mg
5 mg gingerols
Concentrated apple cider vinegar powder (Malus pumila Mill., fruit)
100 mg
Dry extract of turmeric (Curcuma longa L., root)
(95% curcuminoids)
75 mg
71.25 mg curcuminoids
Zinc sulfate (min. 36% zinc)
41.66 mg
15 mg zinc (150% NRV*)
Cholecalciferol (0.25% vitamin D3)
4 mg
10 mcg vitamin D (200% NRV*)
Sodium selenite (min. 45.5% selenium)(26.5% sodium)
0.222 mg
100 mcg selenium (200% NRV*)
* Reference nutritional values
Composition:
L-tyrosine, Ginger extract (Zingiber officinale Roscoe, root) (min. 5% gingerols), concentrated apple cider vinegar juice powder (Malus pumila Mill., fruit), dry turmeric extract (Curcuma longa L., root, 95% curcuminoids), zinc sulfate (min. 36% zinc), cholecalciferol (0.25% vitamin D3), sodium selenite (min. 45.5% selenium)(26.5% sodium), bulking agent (microcrystalline cellulose), anti-caking agents (magnesium salt of fatty acids, silicon dioxide), clear gelatin capsules.
Free from GMOs, allergens and titanium dioxide.
Recommended dosage:
Take 1 capsule of Tirohelp Slim per day.
For optimal effect, it is recommended to take Tirohelp Slim for a period of 3-6 months.
Packaging: 30 capsules
Learn more about the action of the active ingredients in Tirohelp Slim
L-tyrosine
Tyrosine is used by the body in combination with iodine to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Therefore, adding L-tyrosine (one of the natural isomers of the amino acid) to the diet of patients with hypothyroidism is a common practice.
In a 2007 study, Palinkas et al. found that L-tyrosine supplementation increased T3 levels in 85 volunteers exposed to stress. In addition, TSH levels were reduced, high levels of which are commonly associated with hypothyroidism and chronic stress. These results are supported by animal models in which L-tyrosine supplementation improved neuroendocrine function and prevented a decline in thyroid hormone levels under chronic stress (Wang, Z, et al., 2012).
L-tyrosine significantly improves and preserves alertness, psychomotor function, and cognition in extreme situations and in chronic sleep deprivation (Deijen, et al., 1999; Neri, et al., 1995). These effects are likely due to its effects on a number of neurotransmitters and hormones such as melatonin, dopamine, and/or noradrenaline, and could be of clinical relevance for patients suffering from hypothyroidism.
Ginger
Ginger is a spice that has historically been used medicinally in both traditional Chinese medicine and Ayurveda. Today, it is known that many of its beneficial properties are due to its gingerol content, and current evidence regarding its effect on body weight is promising. It has been found that taking ginger with meals contributes to increased energy expenditure, less hunger, and greater satiety from food intake (Mansour et al., 2012). More recent studies suggest that the supplement may increase fat burning, inhibit the formation of new fat, and block the absorption of some calories from food (Ebrahimzadeh Attari et al., 2018).
Current analyses of accumulated experimental data indicate that ginger contributes to a significant reduction in body weight, waist/hip ratio, fasting blood sugar, as well as improving other indicators of metabolic health such as HOMA-IR (insulin resistance index) and "good" HDL cholesterol.
Apple cider vinegar
For thousands of years, apple cider vinegar products have been used for their supposed medicinal properties. They were believed to improve strength, "cleanse" the body, act as antibiotics, and were even relied on as a cure for scurvy.
Today, the main reason people take apple cider vinegar is to lose weight. Early studies in rodents showed that acetic acid can prevent fat storage and speed up metabolism. Human studies have followed, the most cited of which is a Japanese experiment in which 175 participants consumed a drink containing 0, 1, or 2 tablespoons of vinegar daily. After three months, the participants who consumed the most vinegar lost the most weight and registered a significant decrease in triglycerides (Kondo et al., 2009). Another study found that taking apple cider vinegar contributes to fuller feeling after meals and contributes to greater weight loss as a result of dieting (Khezri et al., 2018).
The most recent evidence shows that daily intake of apple cider vinegar for 12 weeks is associated with a significant reduction in a number of anthropometric indicators such as weight, body mass index, waist/hip ratio and body fat, as well as improvements in blood sugar, triglyceride and cholesterol levels (Abou-Khalil, Andary & El-Hayek, 2024).
Curcumin
The antioxidant and anti-inflammatory properties of curcumin have been well studied (Venugopal & Sudheer, 2007). Recently, it was found that thanks to them, standardized turmeric extract can protect the thyroid gland from damage and thus contribute to maintaining stable thyroid hormone levels (Abdelaleem, M, et al., 2018).
Elevated T3 levels can cause increased oxidative stress in the body, and curcumin has been shown to effectively counteract this stress and the associated damage (Samanta, L, et al., 2010).
Benign thyroid nodules are one of the most common endocrine disorders. A recent trial from neighboring Romania showed that curcumin supplementation significantly reduced the size of these nodules after just 6 weeks of supplementation (Stancioiu, F, et al., 2019).
Zinc
The mineral zinc is closely linked to thyroid function in more ways than one. When zinc levels in the body are low, it inhibits the production of THR and TSH, leading to low levels of T4 and T3. Zinc is also a component of the enzyme deiodinase, which converts T4 into functional T3. If the body is deficient or deficient in the mineral, T3 production is impaired or even impossible. (Baltaci, A, et al., 2004; Khanam, S, 2018; Severo, J, et al., 2019). Zinc is also known to be required for the normal functioning of the T3 receptor, and low levels of zinc in this receptor can lead to impaired T3 function (Freake, H, et al. 2001).
Furthermore, low zinc levels are associated with increased autoimmunity – thyroid patients with zinc deficiency have high levels of anti-thyroid antibodies – TPO and Tg (Ertek S, et al. 2010).
Several reports suggest that zinc deficiency is a cause of subclinical hypothyroidism. Supplementing the diet of patients with Down syndrome improves thyroid function (Napolitano, G, et al., 1990). Animal models have shown that hypothyroidism leads to impaired zinc absorption (Chen, S, et al., 2005). Supplemental zinc has beneficial effects on thyroid hormone levels (especially total T3), metabolic rate (Maxwell, C. & Volpe, SL, 2007) and a number of symptoms associated with hypothyroidism, such as depression, decreased mental acuity, hair loss, decreased appetite and skin lesions (Betsy, A, et al., 2013).
A 2015 study of 68 women with hypothyroidism found that zinc intake increased free T3 levels, and the combination of zinc and selenium led to a significant decrease in TSH and an increase in T4 (Mahmoodianfard, S, et al., 2015).
Selenium
Did you know that the thyroid gland is the organ with the highest levels of selenium in the entire body? It is well known that maintaining normal physiological levels of selenium is key for its proper functioning and the prevention of thyroid diseases (Ventura, M., et al., 2017). Low levels of the mineral worsen the negative consequences of iodine deficiency (Arthur, JR, 1991), are associated with subacute thyroiditis, as well as with the most common malignant tumors of the thyroid gland – papillary and follicular carcinoma (Moncayo, R., et al., 2008). A recent cross-sectional study among over 6000 people found that low serum selenium levels are associated with an increased risk of autoimmune thyroiditis and hypothyroidism (Wu, Q., et al., 2015).
It has been repeatedly shown that selenium supplementation can contribute to lowering anti-thyroid antibodies, improving the ultrasound structure of the thyroid gland, and favorably affecting autoimmune thyroiditis, including Hashimoto's (Toulis, KA, et al., 2010; Drutel, A., et al., 2013; Ventura, M., et al., 2017).
Clinical improvement from selenium intake has also been observed in patients with Graves' disease (Drutel, A., et al., 2013), as well as in patients with mild to moderate thyroid-associated ophthalmopathy (Ventura, M., et al., 2017).
Vitamin D
Vitamin D deficiency and insufficiency are common conditions associated with autoimmune thyroid diseases such as Hashimoto’s and Graves’ disease. Furthermore, a number of thyroid tumors have been shown to be associated with impaired vitamin D signaling (Kim, D., 2017). The incidence of vitamin D deficiency is significantly higher in patients with autoimmune thyroiditis and likely plays a role in the pathogenesis of their condition – a significant correlation has been found between the presence of anti-thyroid antibodies and deficiency of the fat-soluble vitamin (Kivity, S., et al., 2010).
Other studies have shown that Hashimoto's patients have elevated levels of the same inflammatory molecules, the harmful effects of which are effectively blocked by adequate serum vitamin D levels (Mikos, H., et al., 2017; Sun, L., et al., 2016; Makariou, S., et al., 2011)
So far, the evidence supporting vitamin D as a potential weapon in the fight against autoimmune thyroid disease is promising. Several clinical trials have found that cholecalciferol supplementation has beneficial effects on anti-thyroid antibody and T4 levels (Chaudhary, S., et al., 2016; Simsek, Y., et al., 2016; Chaudhary, S., 2018).
Contraindications: Do not use during pregnancy, breastfeeding. Do not use in case of hypersensitivity to any of the ingredients. The product is intended for consumption by persons over 18 years of age.
Warnings: Do not exceed the recommended daily dose. Do not use the food supplement as a substitute for a varied diet. Keep out of the reach of small children. Do not use after the expiry date.
Storage conditions: In a cool, dry place.
Due to the presence of raw materials of natural origin in the composition, slight organoleptic differences (color, odor and taste) may be observed in different batches produced, which do not affect the quality of the product.
Manufacturer: Plantapol – Spain, C/G 18, Pol.Malpica – Alfinden, La Puebla Del Alfinden Zaragoza, Spain
Manufactured for: "Naturpharma Bulgaria" EOOD, Sofia, 21 Yanko Sofiyski Str., tel. +35929633359
