NATURPHARMA PEAGREN for the nervous system x 15 caps
Peagren is a NEW non-medicinal solution with palmitoylethanolamide, melatonin and vitamin B2, which contributes to the normal functioning of the nervous system, to reduce the feeling of tiredness and fatigue and shorten the time to fall asleep. It is suitable for long-term use and does not lead to habituation. Composition (in 1 capsule): Palmitoylethanolamide (PEA, micronized amide of saturated fatty acid): 400 mg Vitamin B2 (riboflavin): 8 mg Melatonin: 2 mg Excipients: microcrystalline cellulose (emulsifier), magnesium stearate (anti-caking agent). Recommended dosage: Take 1 capsule of Peagren in the morning about 30 minutes before a meal and 1 capsule in the evening before going to bed for a period of 2 weeks. Then switch to taking 1 capsule in the evening before going to bed for a period of 1-3 months. If necessary, the dose can be increased again to 2 capsules per day, and the duration of administration can be extended. Package: 15 gelatin capsules Primary headaches and migraines: origin and methods of non-drug intervention Primary headaches affect a large percentage of people and have a huge impact on work and personal life. A migraine can last from a few hours to a few days and is characterized by a one-sided, throbbing pain in the head that worsens with physical activity and is accompanied by nausea and irritation from light and noise. It can be preceded by a number of symptoms such as changes in mood and activity, irritability, fatigue, yawning, neck stiffness, and so on. "aura", which is a harbinger of a headache, expressed in a reversible disturbance in vision, speech, sensitivity, etc. After the headache has passed, you may feel unwell accompanied by fatigue, difficulty concentrating and neck stiffness. All these complaints significantly worsen the quality of life for a long period of time. It is believed that migraine has a multifaceted origin, including disorders of the tone and permeability of the blood vessels of the brain, disorders in the cerebral cortex, occurrence of neurogenic inflammation, oxidative stress as well as genetic disorders in the function of cell organelles called mitochondria. Increased irritation of pain nerve endings by substances released during inflammation leads to hypersensitivity and the occurrence of migraine pain. Tension headache is the most common primary headache. He has recurrent episodes of bilateral, tightening, dull pain in the head that is not relieved by usual physical activity. The duration can vary from 30 minutes to several days. The causes can be different, but emotional stress and tension play a major role. Prolonged irritation of painful nerve endings is of great importance for the occurrence and maintenance of pain. Palmitoylethanolamide (PEA) is the body's own substance and belongs to the class of signaling lipids. It is synthesized as needed when there is tissue damage or inflammation so that the body can deal with the disease state. It works by suppressing inflammation around the nerve endings and thereby reducing irritation of pain nerve receptors and activation of pain pathways. PEA also works at the cellular level by blocking the mechanisms leading to inflammation. Another effect of PEA is its effect on the body's cannabinoid system, which is also related to pain reduction. Melatonin has many different physiological functions important for the normal functioning of the central nervous system. It has antioxidant activity, an anti-pain effect, regulates a number of cell receptors that are related to pain and the tone of blood vessels in the brain. It reduces the inflammation and hence the irritation of the nerve endings. It plays a role in regulating sleep-wake cycles and is important for the initiation and maintenance of sleep. Good and sufficient sleep is associated with a lower likelihood of developing chronic migraine, and insufficient and incomplete sleep is a factor in migraine attacks. Vitamin B2 (riboflavin) is a water-soluble B vitamin that is involved in the breakdown of nutrients and the maintenance of epithelium and mucous membranes. One of the main genetic disorders associated with migraines is a malfunction of cellular organelles called mitochondria. They are involved in the regulation of the entry of calcium ions into the cell and the normal functioning of neurons. When these processes are disturbed, increased sensitivity to pain may occur. Riboflavin affects mitochondrial function and protects against migraines. It also affects oxidation and reduction processes in the body and protects against overreaction of pain receptors and the occurrence of headaches. Contraindications: Not to be used during pregnancy, breastfeeding and by children under 6 years of age. Do not use in case of hypersensitivity to any of the ingredients. Due to the presence of melatonin in the preparation and the fact that melatonin is involved in the regulation of sleep, it is recommended that within 1-2 hours after taking Peagren, driving and operating machines should be carried out with caution! Warnings: Do not exceed the recommended daily dose! Peagren should not be used as a substitute for varied nutrition! Keep out of the reach of small children! Manufacturer: Plantapol - Spain, C/G 18, Pol.Malpica - Alfinden, La Puebla Del Alfinden Zaragoza, Spain Distributor: "Naturpharma Bulgaria" EOOD, Sofia, 21 Yanko Sofiyski St., phone +35929633359, info@naturpharmabg .com
