VITAMIN B12 ANKERMANN vitamin B12 1000mcg x 50 tabl
Vitamin B12
VITAMIN B12 ANKERMANN®
1000 MICROGRAMS COATED TABLETS
NAME OF THE MEDICINAL PRODUCT
Vitamin B12 Ankermann 1,000 micrograms coated tablets
RELEASE MODE
Without a doctor's prescription
QUALITATIVE AND QUANTITATIVE COMPOSITION
One coated tablet contains an active substance of 1,000 micrograms of Cyanocobalamin (Vitamin B12 ).
EXCIPIENTS with known effect: lactose, sucrose.
Full list of excipients: povidone K 30, stearic acid, montan-
Glycol Wax, Lactose Monohydrate, Sucrose, Spray Dried Acacia, Talc, Calcium Carbonate, Heavy Kaolin, Titanium Dioxide, White Wax, Macrogol 6000, Macrogolglycerol Hydroxystearate, Sodium Lauryl Sulfate, Croscarmellose Sodium,
hypromellose, hydroxypropylcellulose, medium chain triglycerides.
PHARMACEUTICAL FORM AND PACKAGING
Coated tablet. Original packaging: 50 coated tablets distributed in two blisters of 25 tablets.
EXPIRY DATE AND STORAGE CONDITIONS
Shelf life - 3 years. To be stored at a temperature of up to 25°C.
THERAPEUTIC INDICATIONS
aminosalicylates, proton pump inhibitors and metformin. |
DOSAGE AND METHOD OF ADMINISTRATION
ADULTS
The recommended daily dose is 1,000 micrograms of cyanocobalamin (1 tablet Vitamin B12 Ankermann 1,000 micrograms) for the treatment of mild to moderate vitamin B12 deficiency.
In cases of severe symptoms of vitamin B12 deficiency, it is initially recommended
administration of an injection form. A therapeutic response was observed two months after continuous oral therapy.
CHILDREN AND ADOLESCENTS
Vitamin B12 Ankermann 1,000 micrograms should not be used in children under 6 years of age. It is recommended for children aged 6 and over, as well as for adolescents
cyanocobalamin to be taken orally in a daily dose of 1,000 micrograms - 1 tablet Vitamin B12 Ankermann 1,000 micrograms, provided that patients are able to swallow the tablet.
APPLICATION METHOD
Tablets should be swallowed whole with a sufficient amount of water, preferably in the morning, on an empty stomach
PREGNANCY AND BREAST-FEEDING
Evidence shows that supplementing with vitamin B12 during pregnancy leads to
minimal risk to mother and newborn. Female patients should be advised to consult a doctor or pharmacist before taking this medicine. Vitamin B12
Ankerman 1,000 micrograms film-coated tablets should not be used for the treatment of
megaloblastic anemia of pregnancy, which is caused by folate deficiency. BREAST-FEEDING: Evidence suggests that cyanocobalamin administration is compatible with breast-feeding. The patient should consult a doctor or pharmacist before taking this medicine.
OVERDOSE
Vitamin B12 has a wide therapeutic range and excess amounts are easily eliminated in the urine even at a dose of 100 mg.
Symptoms of poisoning or overdose are not known to occur. In cases of accidental overdose, if necessary, patients should be treated
symptomatically.
CAUSES AND CLINICAL SIGNS OF DEFICIENCY
AVAILABILITY AND NEEDS
The human body cannot synthesize vitamin B12 , and it is absorbed from food. Foods that contain vitamin B12 are liver, kidney, heart, fish, shellfish, milk, egg yolk and meat. Vitamin B12 is used for therapeutic purposes in the form of
cyanocobalamin and/or hydroxocobalamin. They are precursors that the organism
converts to active forms of methylcobalamin and 5-adenosylcobalamin. The required daily requirement of vitamin B12 is about 1 µg.
REASONS FOR DEFICIENCY
Vitamin B12 deficiency may occur due to malabsorption, especially in the elderly (due to malabsorption of cobalamin from food), in patients after
partial gastrectomy or ileostomy or other diseases of the gastrointestinal tract, as well as on a strict vegetarian diet.
CLINICAL SIGNS OF DEFICIENCY
Very often, people with vitamin B12 deficiency have no clinical symptoms or they are discrete and undetectable without biochemical blood tests (subclinical cobalamin deficiency).
In case of impaired or absent absorption of vitamin B12, if the plasma levels
fall below 200 pg/ml , this could lead to the manifestation of clinical symptoms .
The consequences are megaloblastic anemia and neurological deficit of the peripheral and
the central nervous system. Polyneuropathy may occur in combination with lesions of the dorsal columns of the spine and psychological disorders. The early ones
signs of deficiency may include fatigue and pallor, tingling in the hands and feet, unsteady gait, and decreased physical strength. Others may appear
neurological symptoms such as burning sensation, stiffness or pain in the hands and feet,
muscle weakness, confusion and impaired perception.
Symptoms caused by vitamin B12 deficiency can only be corrected by taking vitamin B12.
