NATURPHARMA URIMIL massage gel with arnica, magnesium and devil's claw 50ml
URIMIL GEL / URIMIL GEL is part of the Urimil series, developed with care for the peripheral nervous system. The gel is formulated with five active ingredients with a warming and soothing effect. It can be used for a wide range of neuromuscular conditions such as back and lower back pain, pain and paresthesias in the limbs, rheumatoid arthritis, neuro- and muscle injuries, pain caused by arthritic changes in the joints, muscle fever. After application, it begins to act immediately at the site of application, having a pleasant warming effect. Does not leave greasy stains.
Composition:
- Uridine monophosphate (UMP)
- Arnica extract (Arnica Montana)
- Devil's Claw Extract (Harpagophytum Procumbens)
- Methylsulfonylmethane (MSM)
- Magnesium (magnesium chloride)
Uridine monophosphate (UMP). Topically applied uridine is absorbed through the skin, leading to restoration of nerve structure and function (Hartinger et. al., 2012). Uridine is involved in the synthesis of RNA, proteins and phospholipids, which are key to the construction of cell membranes and nerve cell sheaths. It stimulates the reproduction of nerve cells and the formation of new nerve growths (Manhães et. al., 2017). Pharmacological studies indicate that uridine accelerates and supports neuromuscular recovery and suppresses the conduction of pain in the spinal cord.
Arnica (Arnica montana) is a plant from the Sunflower family that grows mainly in Siberia, Central Europe, Canada and South America. The main active ingredients in the arnica extract are the so-called sesquiterpene lactones. The most important of them is perhaps helenalin , which has an anti-inflammatory (Lyss et. al., 1998), cooling and pain-relieving effect. Applied topically, arnica extract is used to treat osteoarthritis, rheumatoid arthritis, soothe muscle pain, heal bruises, sprains, and wounds.
Devil's claw (Harpagophytum procumbens) is a perennial plant that can only be found in South Africa and is therefore also called African geranium. Its active ingredients in its extract have a pronounced anti-inflammatory and analgesic effect, and its local application leads to improved mobility and quality of life in patients with osteoarthritis, rheumatoid arthritis, tendinitis and low back pain (Wegener, 2000; Denner, 2007).
Methylsulfonylmethane (MSM) is an organic sulfur compound, a natural source of sulfur for the body. MSM has a high ability to pass through cell membranes and affects various cells and tissues. Applied topically, it smoothes and softens the skin, increases energy, circulation and metabolism and accelerates wound healing. It has antioxidant and anti-inflammatory effects (Butawan et. al., 2017), which play an important role in patients with osteoarthritis. MSM is effective in muscle pain after physical exertion due to the delivery of sulfur to the connective tissue and prevention of local inflammation as a result of microtraumas.
Magnesium (Mg) relaxes muscles and reduces pain by blocking NMDA-receptors in nerve cells. Applied topically, it passes through the skin and increases magnesium levels in the body, and these levels depend on the concentration of the drug applied and the time of exposure (Kass et. al., 2017; Chandrasekaran et. al., 2016). It is a cofactor in over 300 enzymatic reactions in the body and is important for muscle contraction, nerve signaling and neuromuscular conduction. This is why magnesium is important in the treatment of peripheral nervous system and musculoskeletal disorders, significantly relieving symptoms such as pain, numbness and tingling (Na et. al., 2011).
Application method:
Rub Urimil gel with gentle massage movements into the affected area until it is completely absorbed by the skin. Apply to clean skin and for maximum effect do not wet the area for at least 3 hours after application. The speed of the effect may vary from person to person. Apply twice daily.
Packaging: 50 ml
Contraindications: Do not use during pregnancy and breastfeeding, do not swallow, do not use on open wounds and mucous membranes, as well as in case of allergy to any of the ingredients.
Manufacturer : PK Benelux BV Vluchtoord 17, 5406 XP Uden, NL
Distributor : "Naturpharma Bulgaria" EOOD, Sofia, 21 Yanko Sofiyski Street,
tel. 02/ 963 33 59, info@naturpharmabg.com
