NATURPHARMA URIMIL massage gel with arnica, magnesium and devil's claw 50ml
URIMIL GEL / URIMIL GEL is part of the Urimil series, developed with care for the peripheral nervous system. The gel is formulated with five active ingredients with a warming and relieving effect. It can be used for a wide range of neuromuscular conditions such as back and waist pain, pain and paresthesia in the limbs, rheumatoid arthritis, neuro- and muscle injuries, pain caused by arthritic changes in the joints, muscle fever. After application, it begins to act immediately at the site of application, providing a pleasant warming effect. It does not leave greasy stains.
Composition:
- Uridine monophosphate (UMP)
- Arnica extract (Arnica Montana)
- Devil's Claw Extract (Harpagophytum Procumbens)
- Methylsulfonylmethane (MSM)
- Magnesium (magnesium chloride)
Uridine monophosphate (UMP). Topically applied uridine is absorbed through the skin, leading to the restoration of nerve structure and function (Hartinger et. al., 2012). Uridine is involved in the synthesis of RNA, proteins and phospholipids, which are key for the construction of cell membranes and nerve cell sheaths. It stimulates the reproduction of nerve cells and the formation of new nerve growths (Manhães et. al., 2017). Pharmacological studies indicate that uridine accelerates and supports neuromuscular recovery and suppresses pain conduction in the spinal cord.
Arnica (Arnica montana) is a plant of the sunflower family, which grows mainly in Siberia, Central Europe, Canada and South America. The main active ingredients in arnica extract are the so-called sesquiterpene lactones. The most important of them is perhaps helenalin , which has anti-inflammatory (Lyss et. al., 1998), cooling and analgesic effects. Applied topically, arnica extract is used to treat osteoarthritis, rheumatoid arthritis, relieve muscle pain, and heal bruises, sprains and wounds.
Devil's claw (Harpagophytum procumbens) is a perennial plant that can only be found in South Africa and is therefore also called African geranium. Its active ingredients in its extract have a strong anti-inflammatory and analgesic effect and its topical application leads to improved mobility and quality of life in patients with osteoarthritis, rheumatoid arthritis, tendonitis and low back pain (Wegener, 2000; Denner, 2007).
Methylsulfonylmethane (MSM) is an organic sulfur compound, a natural source of sulfur for the body. MSM has a high ability to pass through cell membranes and affects various cells and tissues. Applied topically, it smoothes and softens the skin, increases energy, circulation and metabolism, and accelerates wound healing. It has antioxidant and anti-inflammatory effects (Butawan et. al., 2017), which play an important role in patients with osteoarthritis. MSM is effective in muscle pain after physical exertion due to the delivery of sulfur to the connective tissue and the prevention of local inflammation as a result of microtrauma.
Magnesium (Mg) relaxes muscles and reduces pain by blocking NMDA receptors in nerve cells. When applied topically, it passes through the skin and increases magnesium levels in the body, with these levels depending on the concentration of the applied preparation and the time of exposure (Kass et. al., 2017; Chandrasekaran et. al., 2016). It is a cofactor in over 300 enzymatic reactions in the body and is important for muscle contraction, nerve signaling and neuromuscular conduction. Therefore, magnesium is important in the treatment of diseases of the peripheral nervous system and the musculoskeletal system, significantly alleviating symptoms such as pain, numbness and tingling (Na et. al., 2011).
Method of application:
Rub Urimil gel with gentle massage movements into the affected area until completely absorbed by the skin. Apply to clean skin and for maximum effect do not wet the area for at least 3 hours after application. The speed of the effect may vary from person to person. Apply twice daily.
Packaging: 50 ml
Contraindications: Do not use during pregnancy and breastfeeding, do not swallow, do not use on open wounds and mucous membranes, as well as in case of allergy to any of the ingredients.
Manufacturer : PK Benelux BV Vluchtoord 17, 5406 XP Uden, NL
Distributor : "Naturpharma Bulgaria" EOOD, Sofia, 21 Yanko Sofiyski Str.,
tel. 02/ 963 33 59, info@naturpharmabg.com
